Serological Diagnosis of Subclinical Gluten Enteropathy: A Case Presented As Treatment Resistant Osteomalacia
Aynur Başaran1, Kıymet İkbal Karadavut2, Ece Aydoğ3, Aytül Çakcı3
1Zonguldak Karaelmas Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Zonguldak, Türkiye
2Doktor Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi FTR Bölümü, Ankara, Türkiye
3Sağlık Bakanlığı Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi FTR Kliniği, Ankara, Türkiye
Keywords: Gluten enteropathy, osteomalacia, serology
Abstract
Gluten enteropathy is frequently presented with minimal symptoms and signs. Atypical clinical presentation and treatment resistant osteomalacia should be screened for gluten enteropathy. Current serologic diagnostic methods have a high sensitivity and specificity. Serologic screening is recommended even in the absence of clinical symptoms and presence of minor histopathologic findings. In this case we report a patient with treatment resistant osteomalacia due to subclinical gluten enteropathy that responded to gluten free diet. (Rheumatism 2006; 21: 118-20)