Multidrug-Resistant Disseminated Nocardia Farcinica Infection in a Systemic Lupus Erythematosus Patient
Öztürk ATEŞ, 1 Havva CİLAN, 1 Sema OYMAK, 2 Orhan YILDIZ, 3 Oktay OYMAK1
1Department of Nephrology, Medical Faculty of Erciyes University, Kayseri, Turkey
2Department of Pulmonary Medicine, Medical Faculty of Erciyes University, Kayseri, Turkey
3Department of Infection Disease, Medical Faculty of Erciyes University, Kayseri, Turkey
Keywords: Disseminated nocardiosis; Nocardia farcinica; systemic lupus erythematosus
Abstract
Herein, we present a 40-year-old female case who was admitted to our hospital with the complaints of fever and a painful left leg. She had a five-month history of treatment with azathioprine and prednisolone for lupus nephritis. The patient was diagnosed with disseminated nocardiosis (nodular cutaneous lesions, bacteremia, brain abscesses, and a reticulonodular miliary tuberculosis-like infiltration) associated with Nocardia farcinica and was treated using linezolid, netilmicin, and ceftriaxone. This case is important as treatment of Nocardia infections remains week particularly when they involve the central nervous system and when they are sustained by highly drugresistant species such as Nocardia farcinica.